Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis

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Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis.

This work aimed to evaluate the antifungal activity of piroctone olamine in the treatment of intra-abdominal candidiasis in an experimental model using Swiss mice. The mice (n = 6) were infected by intraperitoneal injection of 0.2 ml of C. albicans (10(7)cells/ml in saline). The animals were observed daily for clinical signs and mortality for 14 days. The treatment with piroctone olamine (0.5 m...

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ژورنال

عنوان ژورنال: SpringerPlus

سال: 2016

ISSN: 2193-1801

DOI: 10.1186/s40064-016-2130-8